Serial cloner 1.3 free download

 
Serial Cloner is a molecular biology software. It provides tools with an intuitive interface that assists you in DNA cloning, sequence analysis and visualization. Serial Cloner has been developed to provide a light molecular biology software to both Macintosh and Windows users. Serial Cloner reads and write DNA Strider(tm)-compatible files and import and export files in the universal FASTA format (as well as in pDRAW32 format). Powerful graphical display tools and simple interfaces help the analysis and construction steps (adaptor, PCR, Gateway[tm] cloning) in a very intuitive way.

What's new in this version:

- [New]: Virtual Cutter Window. Predict number and size of fragments upon restriction and simulate gel migration
- [New]: A small Web browser has been added. Not only it allows to surf internet without leaving Serial Cloner but above all it detects automatically a NCBI or an EMBL entry and proposes to parse directly the entry in Serial Cloner format. The comments of the parsed sequence should contain key information.
- [New]: A silent restriction map window has been added to see what site could be introduced in a sequence without changing the translation (not to be used on a full plasmid sequence as it can be quite long to generate).
- [Updated]: A consensus sequence can be extracted after a local alignment.
- [Updated]: Print character size can be set independently of screen character size. 8 pts are usually the best for printing and 12 for viewing on screen.
- [Updated] : Peptides can be numerically selected in the “information” window.
- [Updated] : The DNA sequence corresponding to the selected peptide can be “back” selected.
- [Updated] : Point mutation can be added when preparing a shRNA construct.
- [Addition] : ORF can be found and translated in both strands using the Sequence and Find... windows.
- [Addition]: Alternative start codons can be selected for translation.
- [Addition] : And I also added a function for the PCR experiments. When you select a sequence portion in a sequence window then, if there is a PCR window open a right clic in the sequence window will propose you to use the sequence as forward or reverse primer. It will then directly paste it (anti-paralleled for the reverse primer) in the PCR window.
- [Fixed] : MacOSX (Leopard) - specific crashes.
- [Fixed] : several bugs fixed ( e.g. in Sequence Window, shRNA, Adaptor, Alignment), and interface fixes in particular under Windows (toolbar glitch, behavior when reduced in the Taskbar, etc.). Follow the link and free download Serial Cloner now.  

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